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Literature summary extracted from

  • Nakane, M.; Deguchi, T.
    Purification and properties of guanylate cyclase from the synaptosomal soluble fraction of rat brain (1978), Biochim. Biophys. Acta, 525, 275-285.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.6.1.2 cGMP activation Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.6.1.2 diphosphate
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.6.1.2 0.07
-
 guanyl-imidodiphosphate
-
 Rattus norvegicus
4.6.1.2 0.37
-
 guanyl-(beta,gamma-methylene)-diphosphonate
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.6.1.2 soluble
-
 Rattus norvegicus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.6.1.2 Mn2+
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
4.6.1.2 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.6.1.2
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.6.1.2 brain
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.6.1.2 0.041
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.6.1.2 guanyl-(beta,gamma-methylene)-diphosphate
-
 Rattus norvegicus ?
-
 ?
4.6.1.2 guanyl-imidodiphosphate
-
 Rattus norvegicus ?
-
 ?