Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Nakajima, K.; Hashimoto, T.; Yamada, Y.
    Two tropinone reductases with different stereospecificities are short-chain dehydrogenases evolved from a common ancestor (1993), Proc. Natl. Acad. Sci. USA, 90, 9591-9595.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.236 cDNA coding for TRI and TRII isolated and expressed in Escherichia coli NM522, P29X-encoding gene detected Datura stramonium
1.1.1.236 P29X-encoding gene detected Atropa belladonna

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.236 tropinone + NADPH + H+ Datura stramonium
-
 pseudotropine + NADP+
-
 ?
1.1.1.236 tropinone + NADPH + H+ Atropa belladonna
-
 pseudotropine + NADP+
-
 ?
1.1.1.236 tropinone + NADPH + H+ Hyoscyamus niger
-
 pseudotropine + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.236 Atropa belladonna
-
-
-
1.1.1.236 Datura stramonium
-
-
-
1.1.1.236 Hyoscyamus niger
-
-
-
1.1.1.236 no activity in Nicotiana tabacum
-
 tobacco
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.236
-
 Datura stramonium

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.236 root
-
 Datura stramonium
-
1.1.1.236 root
-
 Atropa belladonna
-
1.1.1.236 root
-
 Hyoscyamus niger
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.236 tropinone + NADPH + H+
-
 Datura stramonium pseudotropine + NADP+
-
 ?
1.1.1.236 tropinone + NADPH + H+
-
 Atropa belladonna pseudotropine + NADP+
-
 ?
1.1.1.236 tropinone + NADPH + H+
-
 Hyoscyamus niger pseudotropine + NADP+
-
 ?