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Literature summary extracted from

  • Nichol, A.W.; Nomura, A.; Hampton, A.
    Studies on phosphate binding sites of inosinic acid dehydrogenase and adenylosuccinate synthetase (1967), Biochemistry, 6, 1008-1015.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.205 Inosine very weak, non-competitive Klebsiella aerogenes
1.1.1.205 Inosine 5'-methylphosphonate very weak, non-competitive Klebsiella aerogenes
1.1.1.205 Inosine 5'-phosphite very weak, non-competitive Klebsiella aerogenes
1.1.1.205 Inosine 5'-phosphofluoridate very weak, non-competitive Klebsiella aerogenes
1.1.1.205 phosphate mixed inhibition kinetics Klebsiella aerogenes
1.1.1.205 ribose 5-phosphate non-competitive Klebsiella aerogenes

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.205 Klebsiella aerogenes
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.205 inosine 5'-phosphate + NAD+ + H2O
-
 Klebsiella aerogenes xanthosine 5'-phosphate + NADH
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.205 NAD+
-
 Klebsiella aerogenes

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.1.1.205 additional information
-
 additional information
-
 Klebsiella aerogenes