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Literature summary extracted from

  • Iwata, N.; Inazu, N.; Takeo, S.; Satoh, T.
    Carbonyl reductases from rat testis and vas deferens. Purification, properties and localization (1990), Eur. J. Biochem., 193, 75-81.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.184 chlorpromazine
-
 Rattus norvegicus
1.1.1.184 CuSO4
-
 Rattus norvegicus
1.1.1.184 dicoumarol
-
 Rattus norvegicus
1.1.1.184 Disulfiram
-
 Rattus norvegicus
1.1.1.184 Ethacrynic acid inhibition of enzyme forms V1, V2 and T3 Rattus norvegicus
1.1.1.184 Furosemide inhibition of V1, V2 and T3 Rattus norvegicus
1.1.1.184 indomethacin
-
 Rattus norvegicus
1.1.1.184 p-hydroxymercuribenzoate
-
 Rattus norvegicus
1.1.1.184 quercetin
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.184 additional information
-
 additional information overview Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.184 32000
-
 x * 32000, enzyme form T1, SDS-PAGE Rattus norvegicus
1.1.1.184 33000
-
 rat, different enzyme forms from testis and vas deferens, SDS-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.184 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.184 2 forms from vas deferens: V1, V2 Rattus norvegicus
1.1.1.184 3 forms from testis: T1, T2, T3 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.184 testis
-
 Rattus norvegicus
-
1.1.1.184 vas deferens mucosal epithelium cells Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.184 4-benzoylpyridine + NADPH
-
 Rattus norvegicus ?
-
 ?
1.1.1.184 additional information overview Rattus norvegicus ?
-
 ?
1.1.1.184 additional information no activity with NADH Rattus norvegicus ?
-
 ?
1.1.1.184 additional information specificity of various enzyme forms Rattus norvegicus ?
-
 ?
1.1.1.184 prostaglandin A1-GSH + NADPH only enzyme forms T3, V1, V2 Rattus norvegicus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
1.1.1.184 ? x * 32000, enzyme form T1, SDS-PAGE Rattus norvegicus
1.1.1.184 ? x * 33000, enzyme forms T2, T3, V1, V2, SDS-PAGE Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.184 NADH no activity with NADH Rattus norvegicus
1.1.1.184 NADPH
-
 Rattus norvegicus