EC Number | Cloned (Comment) | Organism |
---|---|---|
2.6.1.7 | transient expression in HEK-293 cells | Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.6.1.7 | 0.083 | - |
L-kynurenine | pH 8.0, 37°C, recombinant enzyme, cosubstrate 2-oxoglutarate | Rattus norvegicus | |
2.6.1.7 | 1.2 | - |
L-kynurenine | pH 8.0, 37°C, recombinant enzyme, cosubstrate pyruvate | Rattus norvegicus | |
2.6.1.7 | 1.7 | - |
L-kynurenine | pH 8.0, 37°C, cosubstrate pyruvate | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.6.1.7 | cytosol | - |
Rattus norvegicus | 5829 | - |
2.6.1.7 | soluble | - |
Rattus norvegicus | - |
- |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.6.1.7 | 47000 | - |
2 * 47000, SDS-PAGE | Rattus norvegicus |
2.6.1.7 | 90000 | 100000 | gel filtration | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.6.1.7 | Rattus norvegicus | - |
identical to kidney soluble cysteine conjugate beta-lyase also referred to as glutamine transaminase K, K stands for kidney | - |
4.4.1.13 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.6.1.7 | DEAE-Sepharose, phenyl-Sepharose, Superose 12, Mono Q | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.6.1.7 | brain | - |
Rattus norvegicus | - |
2.6.1.7 | kidney | - |
Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.6.1.7 | 0.36 | - |
- |
Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.6.1.7 | L-kynurenine + 2-oxoglutarate | soluble kidney/brain kynurenine aminotransferase has both amino transferase and cysteine conjugate beta-lyase, i.e., glutamine transaminase K activities | Rattus norvegicus | kynurenic acid + L-glutamate + H2O | - |
? | |
2.6.1.7 | L-kynurenine + pyruvate | 100fold higher maximal velocity than with 2-oxoglutarate | Rattus norvegicus | kynurenic acid + L-alanine + H2O | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.6.1.7 | dimer | 2 * 47000, SDS-PAGE | Rattus norvegicus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.6.1.7 | KAT | - |
Rattus norvegicus |
2.6.1.7 | More | identical to kidney soluble cysteine conjugate beta-lyase, EC 2.6.1.64, also referred to as glutamine transaminase K, EC 2.6.1.15, K stands for kidney | Rattus norvegicus |