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Literature summary extracted from

  • Flavin, M.; Segal, A.
    Purification and properties of the cystathionine gamma-cleavage enzyme of Neurospora (1964), J. Biol. Chem., 239, 2220-2227.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.4.1.1 Cys
-
 Neurospora sp.

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.4.1.1 additional information
-
 additional information
-
 Neurospora sp.
4.4.1.1 0.032
-
 L-cystine
-
 Neurospora sp.
4.4.1.1 0.12
-
 meso-cystine
-
 Neurospora sp.
4.4.1.1 0.39
-
 Lanthionine
-
 Neurospora sp.

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.1 Neurospora sp.
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.4.1.1
-
 Neurospora sp.

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.4.1.1 additional information
-
-
 Neurospora sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.1 L-cysteine
-
 Neurospora sp. H2S + NH3 + pyruvate
-
 ?
4.4.1.1 L-cystine + H2O
-
 Neurospora sp. thiocysteine + pyruvate + NH3
-
 ?
4.4.1.1 L-homocystine
-
 Neurospora sp. ?
-
 ?
4.4.1.1 L-homoserine
-
 Neurospora sp. ?
-
 ?
4.4.1.1 Lanthionine
-
 Neurospora sp. ?
-
 ?
4.4.1.1 meso-cystine
-
 Neurospora sp. ?
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
4.4.1.1 pyridoxal 5'-phosphate required Neurospora sp.