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Literature summary extracted from

  • Spector, T.
    Mammalian adenylosuccinate lyase. Participation in the conversion of 2 -dIMP and beta-D-arabinosyl-IMP to adenine nucleotides (1977), Biochim. Biophys. Acta, 481, 741-745.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.3.2.2 2'-deoxy-AMP competitive Mus musculus
4.3.2.2 ADP weak, competitive Mus musculus
4.3.2.2 AMP
-
 Mus musculus
4.3.2.2 arabinosyl-AMP beta-D-arabinosyl-AMP, competitive Mus musculus
4.3.2.2 ATP weak, competitive Mus musculus
4.3.2.2 Mg2+ concentration of Mg2+ approaching that of EDTA Mus musculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.3.2.2 0.003
-
 2'-deoxy-succino-AMP
-
 Mus musculus
4.3.2.2 0.0047
-
 N6-(1,2-dicarboxyethyl)AMP
-
 Mus musculus
4.3.2.2 0.0056
-
 arabinosyl-succino-AMP
-
 Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
4.3.2.2 Mus musculus
-
-
-
4.3.2.2 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.3.2.2
-
 Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.3.2.2 Ehrlich ascites carcinoma cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.3.2.2 2'-deoxy-succino-AMP
-
 Mus musculus 2'-deoxy-AMP + fumarate
-
 ?
4.3.2.2 arabinosyl-succino-AMP i.e. beta-D-arabinosyladenylosuccinate Mus musculus arabinosyl-AMP + ? beta-D-arabinosyl-AMP ?