EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
4.3.1.3 | GSH | increases at concentrations below 5 mM, pH 7.4 | Cavia porcellus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.3.1.3 | 5,5'-dithiobis(2-nitrobenzoic acid) | - |
Cavia porcellus | |
4.3.1.3 | dithiothreitol | 20 mM, liver and epidermal enzyme, restored by addition with Zn2+ | Cavia porcellus | |
4.3.1.3 | EDTA | 0.04 mM, liver and epidermal enzyme, restored by incubation with Zn2+ | Cavia porcellus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.3.1.3 | 0.36 | - |
L-histidine | pH 9.2 and pH 7.0, epidermal enzyme | Cavia porcellus | |
4.3.1.3 | 0.55 | - |
L-histidine | pH 9.2, liver enzyme | Cavia porcellus | |
4.3.1.3 | 1 | - |
L-histidine | pH 7.0, liver enzyme | Cavia porcellus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
4.3.1.3 | Zn2+ | - |
Cavia porcellus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
4.3.1.3 | 220000 | - |
gel-permeation chromatography, liver and epidermis enzyme | Cavia porcellus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.3.1.3 | Cavia porcellus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.3.1.3 | epidermis | isoenzyme | Cavia porcellus | - |
4.3.1.3 | epidermis | stratum granulosum | Cavia porcellus | - |
4.3.1.3 | epidermis | stratum corneum | Cavia porcellus | - |
4.3.1.3 | liver | isoenzyme | Cavia porcellus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.3.1.3 | L-histidine | natural substrate | Cavia porcellus | urocanate + NH3 | - |
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