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Literature summary extracted from

  • Unkeless, J.C.; Goldman, P.
    Thermodynamic and kinetic aspects of the reaction of gamma-fluoroglutamate with D-glutamate cyclase (1971), J. Biol. Chem., 246, 2354-2359.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.2.1.48 90
-
 5-oxo-D-proline
-
 Mus musculus
4.2.1.48 200
-
 D-glutamate
-
 Mus musculus
4.2.1.48 200
-
 cis-D-3-fluoro-2-pyrrolidone-5-carboxylate
-
 Mus musculus
4.2.1.48 1500
-
 trans-D-3-fluoro-2-pyrrolidone-5-carboxylate
-
 Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.48 Mus musculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.1.48
-
 Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.1.48 liver
-
 Mus musculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.2.1.48 580
-
-
 Mus musculus

Storage Stability

EC Number Storage Stability Organism
4.2.1.48 -196°C Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.48 cis-3-fluoro-2-pyrrolidone-5-carboxylate + H2O
-
 Mus musculus gamma-fluoroglutamate
-
 ?
4.2.1.48 D-glutamate
-
 Mus musculus 5-oxo-D-proline + H2O
-
 ?
4.2.1.48 erythro-gamma-fluoroglutamate
-
 Mus musculus 3-fluoro-2-pyrrolidone-5-carboxylate + H2O
-
 ?
4.2.1.48 threo-gamma-fluoroglutamate
-
 Mus musculus 3-fluoro-2-pyrrolidone-5-carboxylate + H2O
-
 ?
4.2.1.48 trans-3-fluoro-2-pyrrolidone-5-carboxylate + H2O
-
 Mus musculus gamma-fluoroglutamate
-
 ?
4.2.1.48 trans-D-3-fluoro-2-pyrrolidone-5-carboxylate + H2O
-
 Mus musculus gamma-fluoroglutamate
-
 ?