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Literature summary extracted from

  • Livingstone-Zatchej, M.; Meier, A.; Suter, B.; Thoma, F.
    RNA polymerase II transcription inhibits DNA repair by photolyase in the transcribed strand of active yeast genes (1997), Nucleic Acids Res., 25, 3795-3800.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
4.1.99.3 Saccharomyces cerevisiae
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.99.3 cyclobutadipyrimidine in DNA the enzyme preferentially repairs the non-transcribed strands of the URA3 and HIS3 genes in minichromosomes, repair of the non-transcribed strand is more quickly in the active gene than in the repressed gene indicating that transcription dependent disruption of chromatin facilitates repair of an active gene Saccharomyces cerevisiae pyrimidine residues in DNA
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Cofactor

EC Number Cofactor Comment Organism Structure
4.1.99.3 FADH2
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Saccharomyces cerevisiae