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Literature summary extracted from

  • Goto, Y.; Zalkin, H.; Keim, P.S.; Heinrikson, R.L.
    Properties of anthranilate synthetase component II from Pseudomonas putida (1976), J. Biol. Chem., 251, 941-949.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.3.27 iodoacetamide irreversible, Gln protects Pseudomonas putida
4.1.3.27 L-2-Amino-4-oxo-5-chloropentanoic acid irreversible, Gln protects Pseudomonas putida

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.3.27 0.009
-
chorismate anthranilate formation Pseudomonas putida
4.1.3.27 0.025
-
chorismate chorismate-dependent glutaminase activity Pseudomonas putida
4.1.3.27 1.4
-
Gln anthranilate formation Pseudomonas putida
4.1.3.27 5.6
-
Gln chorismate-dependent glutaminase activity Pseudomonas putida

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.3.27 additional information Pseudomonas putida initial steps in glutamine utilization ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
4.1.3.27 Pseudomonas putida
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.3.27
-
Pseudomonas putida

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.3.27 additional information
-
-
Pseudomonas putida

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.3.27 chorismate + L-Gln
-
Pseudomonas putida anthranilate + pyruvate + L-glutamate
-
?
4.1.3.27 additional information active site residue that forms the covalent gamma-glutamyl-AS II intermediate is Cys Pseudomonas putida ?
-
?
4.1.3.27 additional information initial steps in glutamine utilization Pseudomonas putida ?
-
?