BRENDA - Enzyme Database

Specificity of 4-chlorobenzoyl coenzyme A dehalogenase catalyzed dehalogenation of halogenated aromatics

Liang, P.H.; Yang, G.; Dunaway-Mariano, D.; Biochemistry 32, 12245-12250 (1993)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
3.8.1.7
-
Pseudomonas sp.
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.8.1.7
4-Chlorobenzoate
-
Pseudomonas sp.
3.8.1.7
benzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
CoA
-
Pseudomonas sp.
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.8.1.7
0.0037
-
4-chlorobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.0042
-
4-bromobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.0055
-
4-chloro-3-nitrobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.0065
-
4-iodobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.0104
-
2,4-dichlorobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.03
-
4-chloro-2-nitrobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.042
-
3,4-dichlorobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.075
-
4-chloro-3-methylbenzoyl-CoA
-
Pseudomonas sp.
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.8.1.7
Pseudomonas sp.
-
; recombinant enzyme expressed in Escherichia coli
-
3.8.1.7
Pseudomonas sp. CBS-3
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.8.1.7
2,4-dichlorobenzoyl-CoA + H2O
-
33078
Pseudomonas sp.
?
-
-
-
-
3.8.1.7
2,4-dichlorobenzoyl-CoA + H2O
-
33078
Pseudomonas sp. CBS-3
?
-
-
-
-
3.8.1.7
3,4-dichlorobenzoyl-CoA + H2O
-
33078
Pseudomonas sp.
?
-
-
-
-
3.8.1.7
3,4-dichlorobenzoyl-CoA + H2O
-
33078
Pseudomonas sp. CBS-3
?
-
-
-
-
3.8.1.7
4-bromobenzoyl-CoA + H2O
-
33078
Pseudomonas sp.
4-hydroxybenzoyl-CoA + bromide
-
-
-
-
3.8.1.7
4-bromobenzoyl-CoA + H2O
-
33078
Pseudomonas sp. CBS-3
4-hydroxybenzoyl-CoA + bromide
-
-
-
-
3.8.1.7
4-chloro-2-nitrobenzoyl-CoA + H2O
-
33078
Pseudomonas sp.
?
-
-
-
-
3.8.1.7
4-chloro-3-methylbenzoyl-CoA + H2O
-
33078
Pseudomonas sp.
?
-
-
-
-
3.8.1.7
4-chloro-3-nitrobenzoyl-CoA + H2O
-
33078
Pseudomonas sp.
?
-
-
-
-
3.8.1.7
4-chlorobenzoyl-CoA + H2O
-
33078
Pseudomonas sp.
4-hydroxybenzoyl-CoA + chloride
-
-
-
-
3.8.1.7
4-chlorobenzoyl-CoA + H2O
-
33078
Pseudomonas sp. CBS-3
4-hydroxybenzoyl-CoA + chloride
-
-
-
-
3.8.1.7
4-iodobenzoyl-CoA + H2O
-
33078
Pseudomonas sp.
4-hydroxybenzoyl-CoA + iodide
-
-
-
-
3.8.1.7
4-iodobenzoyl-CoA + H2O
-
33078
Pseudomonas sp. CBS-3
4-hydroxybenzoyl-CoA + iodide
-
-
-
-
Turnover Number [1/s]
EC Number
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
3.8.1.7
0.052
-
3,4-dichlorobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.063
-
4-chloro-2-nitrobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.511
-
2,4-dichlorobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.6
-
chlorobenzoyl-CoA
multiple turnovers
Pseudomonas sp.
3.8.1.7
1.1
-
4-iodobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
1.4
-
4-bromobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
2
-
chlorobenzoyl-CoA
single turnover
Pseudomonas sp.
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
3.8.1.7
-
Pseudomonas sp.
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.8.1.7
4-Chlorobenzoate
-
Pseudomonas sp.
3.8.1.7
benzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
CoA
-
Pseudomonas sp.
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
3.8.1.7
0.0037
-
4-chlorobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.0042
-
4-bromobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.0055
-
4-chloro-3-nitrobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.0065
-
4-iodobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.0104
-
2,4-dichlorobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.03
-
4-chloro-2-nitrobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.042
-
3,4-dichlorobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.075
-
4-chloro-3-methylbenzoyl-CoA
-
Pseudomonas sp.
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.8.1.7
2,4-dichlorobenzoyl-CoA + H2O
-
33078
Pseudomonas sp.
?
-
-
-
-
3.8.1.7
2,4-dichlorobenzoyl-CoA + H2O
-
33078
Pseudomonas sp. CBS-3
?
-
-
-
-
3.8.1.7
3,4-dichlorobenzoyl-CoA + H2O
-
33078
Pseudomonas sp.
?
-
-
-
-
3.8.1.7
3,4-dichlorobenzoyl-CoA + H2O
-
33078
Pseudomonas sp. CBS-3
?
-
-
-
-
3.8.1.7
4-bromobenzoyl-CoA + H2O
-
33078
Pseudomonas sp.
4-hydroxybenzoyl-CoA + bromide
-
-
-
-
3.8.1.7
4-bromobenzoyl-CoA + H2O
-
33078
Pseudomonas sp. CBS-3
4-hydroxybenzoyl-CoA + bromide
-
-
-
-
3.8.1.7
4-chloro-2-nitrobenzoyl-CoA + H2O
-
33078
Pseudomonas sp.
?
-
-
-
-
3.8.1.7
4-chloro-3-methylbenzoyl-CoA + H2O
-
33078
Pseudomonas sp.
?
-
-
-
-
3.8.1.7
4-chloro-3-nitrobenzoyl-CoA + H2O
-
33078
Pseudomonas sp.
?
-
-
-
-
3.8.1.7
4-chlorobenzoyl-CoA + H2O
-
33078
Pseudomonas sp.
4-hydroxybenzoyl-CoA + chloride
-
-
-
-
3.8.1.7
4-chlorobenzoyl-CoA + H2O
-
33078
Pseudomonas sp. CBS-3
4-hydroxybenzoyl-CoA + chloride
-
-
-
-
3.8.1.7
4-iodobenzoyl-CoA + H2O
-
33078
Pseudomonas sp.
4-hydroxybenzoyl-CoA + iodide
-
-
-
-
3.8.1.7
4-iodobenzoyl-CoA + H2O
-
33078
Pseudomonas sp. CBS-3
4-hydroxybenzoyl-CoA + iodide
-
-
-
-
Turnover Number [1/s] (protein specific)
EC Number
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
3.8.1.7
0.052
-
3,4-dichlorobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.063
-
4-chloro-2-nitrobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.511
-
2,4-dichlorobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
0.6
-
chlorobenzoyl-CoA
multiple turnovers
Pseudomonas sp.
3.8.1.7
1.1
-
4-iodobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
1.4
-
4-bromobenzoyl-CoA
-
Pseudomonas sp.
3.8.1.7
2
-
chlorobenzoyl-CoA
single turnover
Pseudomonas sp.