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Literature summary extracted from
- Substrate specificity of the human splenic non-specific soluble beta-glucosidase (1983), Eur. J. Biochem., 133, 283-287.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.2.1.21 | 4-aminothiophenyl-beta-D-xyloside | 25% inhibition at 3 mM | Homo sapiens |  |
| 3.2.1.21 | 4-nitrophenyl-beta-D-galactopyranoside | 25% inhibition at 3 mM | Homo sapiens | |
| 3.2.1.21 | 4-nitrophenyl-beta-D-glucopyranoside | 45% inhibition at 3 mM | Homo sapiens | |
| 3.2.1.21 | 4-nitrophenyl-beta-D-mannopyranoside | 94% inhibition at 3 mM | Homo sapiens | |
| 3.2.1.21 | 4-nitrophenyl-beta-D-xyloside | 80% inhibition at 3 mM | Homo sapiens | |
| 3.2.1.21 | 4-nitrothiophenyl beta-D-galactopyranoside | 30% inhibition at 3 mM | Homo sapiens | |
| 3.2.1.21 | 4-nitrothiophenyl beta-D-glucopyranoside | 20% inhibition at 3 mM | Homo sapiens | |
| 3.2.1.21 | cetyltrimethyl-ammoniumbromide | complete inhibition at 27 mM | Homo sapiens | |
| 3.2.1.21 | D-glucono-1,4-lactone | 10% inhibition at 3 mM | Homo sapiens | |
| 3.2.1.21 | D-glucono-1,5-lactone | 90% inhibition at 3 mM | Homo sapiens | |
| 3.2.1.21 | delta-valerolactone | 30% inhibition at 3 mM | Homo sapiens | |
| 3.2.1.21 | m-nitrophenyl-beta-D-galactopyranoside | 17% inhibition at 3 mM | Homo sapiens | |
| 3.2.1.21 | taurocholic acid | 90% inhibition at 18 mM | Homo sapiens | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.2.1.21 | 0.1 | - |
4-methylumbelliferyl-beta-D-glucoside | - |
Homo sapiens | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.2.1.21 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.2.1.21 | partial | Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.2.1.21 | spleen | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.2.1.21 | 4-methylumbelliferyl-beta-D-glucoside + H2O | - |
Homo sapiens | 4-methylumbelliferone + beta-D-glucose | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.2.1.21 | 5.7 | - |
- |
Homo sapiens |
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Release 2023.1 (January 2023)
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