BRENDA - Enzyme Database show

Design of new potential 5-lipoxygenase inhibitors. Dual thromboxane synthase inhibitors, and thromboxane A2 receptor antagonists by AM1

Albuquerque, M.G.; Rodrigues.C.R.; Bicca de Alencastro, R.; Int. J. Quantum Chem. 22, 181-190 (1995)
No PubMed abstract available

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
5.3.99.5
additional information
design of new potential dual blocker which inhibits thromboxane synthase and antagonizes thromboxane A2 receptor
Mammalia
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.3.99.5
Mammalia
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.5
Prostaglandin H2
i.e. PGH2
3199
Mammalia
Thromboxane B2 + 12(L)-hydroxy-5,8,10-heptadecatrienoic acid
-
-
-
-
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
5.3.99.5
additional information
design of new potential dual blocker which inhibits thromboxane synthase and antagonizes thromboxane A2 receptor
Mammalia
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.5
Prostaglandin H2
i.e. PGH2
3199
Mammalia
Thromboxane B2 + 12(L)-hydroxy-5,8,10-heptadecatrienoic acid
-
-
-
-