BRENDA - Enzyme Database show

Thromboxane A2 synthetase inhibition suppresses cough induced by angiotensin converting enzyme inhibitors

Umemura, K.; Nakashima, M.; Saruta, T.; Life Sci. 60, 1583-1588 (1997)

Data extracted from this reference:

Application
EC Number
Application
Commentary
Organism
5.3.99.5
medicine
thromboxane A2 may somehow mediate coughing induced by the angiotensin converting enzyme inhibitors. Patients on angiotensin converting enzyme inhibitors who develop cough may benefit from thromboxane A2 synthetase inhibitors
Homo sapiens
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.3.99.5
Homo sapiens
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.5
Prostaglandin H2
i.e. PGH2
3185
Homo sapiens
Thromboxane B2 + 12(L)-hydroxy-5,8,10-heptadecatrienoic acid
-
-
-
-
Application (protein specific)
EC Number
Application
Commentary
Organism
5.3.99.5
medicine
thromboxane A2 may somehow mediate coughing induced by the angiotensin converting enzyme inhibitors. Patients on angiotensin converting enzyme inhibitors who develop cough may benefit from thromboxane A2 synthetase inhibitors
Homo sapiens
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.5
Prostaglandin H2
i.e. PGH2
3185
Homo sapiens
Thromboxane B2 + 12(L)-hydroxy-5,8,10-heptadecatrienoic acid
-
-
-
-