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Literature summary extracted from
- Production of platelet thromboxane A2 inactivates purified human platelet thromboxane synthase (1986), Biochem. J., 233, 637-641.
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 5.3.99.5 | immobilized enzyme is inactivated at pH 3.0 | Homo sapiens |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.3.99.5 | 1-Benzylimidazole | immobilized enzyme | Homo sapiens |  |
| 5.3.99.5 | Sodium 5-(3'-pyridinylmethyl)benzofuran-2-carboxylate | immobilized enzyme | Homo sapiens | |
| 5.3.99.5 | thromboxane A2 | the production of thromboxane A2 by the enzyme is self-limiting, the enzyme is inactivated during the reaction | Homo sapiens | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.3.99.5 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.3.99.5 | partial | Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.3.99.5 | platelet | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 5.3.99.5 | 0.259 | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.3.99.5 | Prostaglandin H2 | i.e. PGH2 | Homo sapiens | thromboxane B2 + 12(L)-hydroxy-5,8,10-heptadecatrienoic acid | - |
? | |
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