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Literature summary extracted from

  • Yokono, K.; Imamura, Y.; Shii, K.; Sakai, H.; Baba, S.
    Purification and characterization of insulin-degrading enzyme from pig skeletal muscle (1981), Endocrinology, 108, 1527-1532.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.56 Proinsulin competitive Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.24.56 0.00007
-
 Insulin
-
 Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.24.56 60000
-
 x * 60000, pig, SDS-PAGE Sus scrofa
3.4.24.56 135000
-
 pig, gel filtration Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.56 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.56
-
 Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.56 skeletal muscle
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.56 Glucagon + H2O
-
 Sus scrofa Hydrolyzed glucagon
-
 ?
3.4.24.56 Insulin + H2O not: individual A and B-chains of insulin Sus scrofa Hydrolyzed insulin
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.24.56 ? x * 60000, pig, SDS-PAGE Sus scrofa