Literature summary extracted from

Matsumoto, H.; Naraba, H.; Murakami, M.; Kudo, I.; Yamaki, K.; Ueno, A.; Oh-ishi, S.
Concordant induction of prostaglandin E2 synthase with cyclooxygenase-2 leads to preferred production of prostaglandin E2 over thromboxane and prostaglandin D2 in lipopolysaccharide-stimulated rat peritoneal macrophages (1997), Biochem. Biophys. Res. Commun., 230, 110-114.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
5.3.99.3	additional information	Rattus norvegicus	concordant induction of terminal prostaglandin E2 synthase with cyclooxygenase-2 leads to the preferred production of prostaglandin E2 over thromboxane B2 and prostaglandin D2, by lipopolysaccharide-stimulated macrophages	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
5.3.99.3	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
5.3.99.3	peritoneal macrophage	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5.3.99.3	additional information	concordant induction of terminal prostaglandin E2 synthase with cyclooxygenase-2 leads to the preferred production of prostaglandin E2 over thromboxane B2 and prostaglandin D2, by lipopolysaccharide-stimulated macrophages	Rattus norvegicus	?	-	?

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Release 2023.1 (January 2023)