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Literature summary extracted from

  • Drapeau, G.R.
    Role of metalloprotease in activation of the precursor of staphylococcal protease (1978), J. Bacteriol., 136, 607-613.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.29 1,10-phenanthroline
-
 Staphylococcus aureus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.24.29 Co2+ reactivates 1,10-phenanthroline inactivated enzyme with 160% of the activity of the native enzyme Staphylococcus aureus
3.4.24.29 Zn2+ reactivates 1,10-phenanthroline inactivated enzyme Staphylococcus aureus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.24.29 38000
-
 x * 38000, Staphylococcus aureus, SDS-PAGE Staphylococcus aureus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.29 additional information Staphylococcus aureus activates the precursor of another protease secreted by the same organism, staphylococcal protease ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.29 Staphylococcus aureus
-
 mutant of strain V8
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.29
-
 Staphylococcus aureus

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.24.29 additional information
-
-
 Staphylococcus aureus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.29 additional information specificity for peptide bonds on the N-terminal side of large hydrophobic residues Staphylococcus aureus ?
-
 ?
3.4.24.29 additional information activates the precursor of another protease secreted by the same organism, staphylococcal protease Staphylococcus aureus ?
-
 ?
3.4.24.29 Nalpha-Furylacryloyl-Gly-Leu amide + H2O
-
 Staphylococcus aureus ?
-
 ?
3.4.24.29 Oxidized insulin B-chain + H2O cleaves at His5-Leu6, His10-Leu11, Ala14-Leu15, Tyr16-Leu17, Gly23-Phe24, Phe25-Tyr26 Staphylococcus aureus Hydrolyzed oxidized insulin
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.24.29 ? x * 38000, Staphylococcus aureus, SDS-PAGE Staphylococcus aureus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.24.29 7
-
 N-alpha-furylacryloyl-Gly-Leu amide Staphylococcus aureus