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Literature summary extracted from

  • Woessner, J.F.; Taplin, C.J.
    Purification and properties of a small latent matrix metalloproteinase of the rat uterus (1988), J. Biol. Chem., 263, 16918-16925.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.23 1,10-phenanthroline
-
 Rattus norvegicus
3.4.24.23 DTT
-
 Rattus norvegicus
3.4.24.23 additional information not: phosphoramidon; Zincov Rattus norvegicus
3.4.24.23 Ovostatin
-
 Rattus norvegicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.24.23 Ca2+ required Rattus norvegicus
3.4.24.23 Co2+ partial activation Rattus norvegicus
3.4.24.23 Sr2+ partial activation Rattus norvegicus
3.4.24.23 Zinc zinc is the metal at the active center Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.24.23 14000
-
 rat, active form, gel filtration Rattus norvegicus
3.4.24.23 19000
-
 x * 19000, active form, SDS/DTT-PAGE Rattus norvegicus
3.4.24.23 26000
-
 rat, latent form, gel filtration Rattus norvegicus
3.4.24.23 28000
-
 x * 28000, latent form, SDS/DTT-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.23 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.23
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.23 uterus
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.23 Azocoll + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.24.23 Dinitrophenyl-Pro-Leu-Gly-Ile-Ala-Gly-Pro-D-Arg + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.24.23 Fibronectin + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.24.23 Gelatin + H2O type III Rattus norvegicus ?
-
 ?
3.4.24.23 Gelatin + H2O type IV Rattus norvegicus ?
-
 ?
3.4.24.23 Gelatin + H2O type V Rattus norvegicus ?
-
 ?
3.4.24.23 Gelatin + H2O digests the alpha2(I) chain of gelatin in preference to the alpha1(I) chain Rattus norvegicus ?
-
 ?
3.4.24.23 Gelatin + H2O type I Rattus norvegicus ?
-
 ?
3.4.24.23 Insulin B-chain + H2O cleavage at 2 points: Ala14-Leu15 and Tyr16-Leu17 Rattus norvegicus ?
-
 ?
3.4.24.23 additional information phenylazo-Pro-Leu-Gly-Pro-D-Arg Rattus norvegicus ?
-
 ?
3.4.24.23 additional information collagens of type I, III or V Rattus norvegicus ?
-
 ?
3.4.24.23 Proteoglycan + H2O
-
 Rattus norvegicus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.24.23 ? x * 19000, active form, SDS/DTT-PAGE Rattus norvegicus
3.4.24.23 ? x * 28000, latent form, SDS/DTT-PAGE Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.24.23 7
-
 azocoll, proteoglycan Rattus norvegicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.4.24.23 5.5 8.8 5.5: about 30% of activity maximum, 8.8: about 40% of activity maximum Rattus norvegicus