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Literature summary extracted from

  • Hayaishi, O.
    Prostaglandin D synthase, beta-trace and sleep (1998), Recent Adv. Prostaglandin Thromboxane Leukotriene Res., 1998, 347-350.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
5.3.99.2 glutathione
-
Homo sapiens
5.3.99.2 glutathione the spleen-type PGD synthase is a kind of glutathione S-transferase and therefore requires glutathione for activity Rattus norvegicus
5.3.99.2 glutathione required for activity of spleen enzyme, not required for brain enzyme Rattus norvegicus

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.3.99.2
-
Homo sapiens
5.3.99.2
-
Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.3.99.2 Se4+
-
Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
5.3.99.2 Homo sapiens
-
-
-
5.3.99.2 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.3.99.2 brain
-
Homo sapiens
-
5.3.99.2 brain prostaglandin-H2 D-isomerase is produced in the membrane system surrounding the brain and is secreted into the cerebrospinal fluid to become beta-trace Rattus norvegicus
-