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Literature summary extracted from

  • Kessler, E.; Adar, R.; Goldberg, B.; Niece, R.
    Partial purification and characterization of a procollagen C-proteinase from the culture medium of mouse fibroblasts (1986), Coll. Relat. Res., 6, 249-266.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.19 Amines
-
 Mus musculus
3.4.24.19 Blood serum
-
 Mus musculus
3.4.24.19 DTT
-
 Mus musculus
3.4.24.19 leupeptin not Mus musculus
3.4.24.19 metal chelators
-
 Mus musculus
3.4.24.19 additional information not: inhibitors of serine Mus musculus
3.4.24.19 NEM
-
 Mus musculus
3.4.24.19 pepstatin not Mus musculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.24.19 125000
-
 mouse, gel filtration Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.19 Mus musculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.19
-
 Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.19 culture medium of cultured mouse fibroblasts Mus musculus
-
3.4.24.19 tendon
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.19 Procollagen type I + H2O cleavage occurs at the physiological site, i.e. at the specific Ala-Asp bond in the pro-alpha1(I) and pro-alpha2(I) chains, and at the specific Gly-Asp bond in the pro-alpha1(III) Mus musculus Type I pNcollagen + C-propeptides pNcollagen is an intermediate in the processing of procollagen to collagen containing the amino propeptides but not the carboxyl propeptides ?
3.4.24.19 Procollagen type II + H2O
-
 Mus musculus Type II pNcollagen + C-propeptides pNcollagen is an intermediate in the processing of procollagen to collagen containing the amino propeptides but not the carboxyl propeptides ?
3.4.24.19 Procollagen type III + H2O
-
 Mus musculus Type III pNcollagen + C-propeptides pNcollagen is an intermediate in the processing of procollagen to collagen containing the amino propeptides but not the carboxyl propeptides ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.24.19 8.5
-
-
 Mus musculus