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Literature summary extracted from

  • Hojima, Y.; Behta, B.; Romanic, A.M.; Prockop, D.J.
    Cadmium ions inhibit procollagen C-proteinase and cupric ions inhibit procollagen N-proteinase (1994), Matrix Biol., 14, 113-120.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.14 1,10-phenanthroline
-
 Gallus gallus
3.4.24.14 Cd2+ moderate inhibitor Gallus gallus
3.4.24.14 Cu2+ strong inhibitor Gallus gallus
3.4.24.14 EDTA
-
 Gallus gallus
3.4.24.14 Ni2+
-
 Gallus gallus
3.4.24.14 Zn2+
-
 Gallus gallus
3.4.24.19 Cd2+
-
 Gallus gallus
3.4.24.19 CuCl2
-
 Gallus gallus
3.4.24.19 ZnCl2
-
 Gallus gallus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.24.14 Ca2+ required for maximal activity Gallus gallus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.14 procollagen I + H2O Gallus gallus
-
 ?
-
 ?
3.4.24.14 procollagen II + H2O Gallus gallus
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.14 Gallus gallus
-
-
-
3.4.24.19 Gallus gallus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.14
-
 Gallus gallus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.14 sternum
-
 Gallus gallus
-
3.4.24.14 tendon
-
 Gallus gallus
-
3.4.24.19 tendon
-
 Gallus gallus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.14 procollagen I + H2O
-
 Gallus gallus pCCollagen I + oligopeptide partially processed procollagen containing only the C-propeptides ?
3.4.24.14 procollagen I + H2O
-
 Gallus gallus ?
-
 ?
3.4.24.14 procollagen II + H2O
-
 Gallus gallus pCCollagen II + oligopeptide partially processed procollagen containing only the C-propeptides ?
3.4.24.14 procollagen II + H2O
-
 Gallus gallus ?
-
 ?
3.4.24.19 Procollagen type I + H2O
-
 Gallus gallus Type I pNcollagen + C-propeptides
-
 ?
3.4.24.19 Procollagen type II + H2O cleavage of C-terminal extension propeptide Gallus gallus Type II pNcollagen + C-propeptides
-
 ?
3.4.24.19 Procollagen type III + H2O cleavage of C-terminal extension propeptide Gallus gallus Type III pNcollagen + C-propeptides
-
 ?