EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.23.17 | Diazoacetylnorleucine methyl ester | - |
Bos taurus | |
3.4.23.17 | leupeptin | - |
Bos taurus | |
3.4.23.17 | pepstatin A | - |
Bos taurus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.23.17 | 0.0019 | - |
beta-Lipotropin | human substrate, cleavage at Lys37-Lys38 | Bos taurus | |
3.4.23.17 | 0.0025 | - |
beta-Lipotropin | human substrate, cleavage at Lys57-Arg58 | Bos taurus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.23.17 | Bos taurus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.23.17 | hypophysis | intermediate | Bos taurus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.23.17 | Human beta-lipotropin + H2O | cleavage at two of the three pairs of basic residues of human beta-lipotropin, at Lys37-Lys38 and Lys57-Arg58, but not at Lys86-Lys87, the cleavage at Lys57-Arg58 occurs primarily between these basic residues | Bos taurus | More | at enzyme concentration of 20 ng/0.1 ml: gamma-lipotropin + a beta-melanotropin linked to beta-endorphin intermediate + beta-endorpin, at enzyme concentration of 40 ng/0.1 ml: complete cleavage to yield beta-endorphin + beta-melanotrophin | ? | |
3.4.23.17 | Pro-opiomelanocortin + H2O | - |
Bos taurus | Adrenocorticotropin + beta-lipotropin | - |
? |