EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.4.22.24 | EDTA | activation | Rattus norvegicus | |
3.4.22.24 | sulfhydryl compounds | activation | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.22.24 | antipain | - |
Rattus norvegicus | |
3.4.22.24 | iodoacetamide | - |
Rattus norvegicus | |
3.4.22.24 | iodoacetate | - |
Rattus norvegicus | |
3.4.22.24 | leupeptin | - |
Rattus norvegicus | |
3.4.22.24 | additional information | no inhibition by pepstatin A, soybean trypsin inhibitor | Rattus norvegicus | |
3.4.22.24 | N-ethylmaleimide | - |
Rattus norvegicus | |
3.4.22.24 | PCMB | - |
Rattus norvegicus | |
3.4.22.24 | PMSF | weak | Rattus norvegicus | |
3.4.22.24 | tosyl-L-lysine chloromethyl ketone | - |
Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.4.22.24 | lysosome | - |
Rattus norvegicus | 5764 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.4.22.24 | 33500 | - |
gel filtration | Rattus norvegicus |
3.4.22.24 | 33500 | - |
rat, liver | Rattus norvegicus |
3.4.22.24 | 35000 | - |
1 * 35000, liver | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.22.24 | Tyrosine aminotransferase + H2O | Rattus norvegicus | involved in generation of isozymic forms of tyrosine transferase | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.22.24 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.4.22.24 | kidney | Rattus norvegicus |
3.4.22.24 | liver | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.22.24 | HTC cell | - |
Rattus norvegicus | - |
3.4.22.24 | kidney | - |
Rattus norvegicus | - |
3.4.22.24 | liver | - |
Rattus norvegicus | - |
3.4.22.24 | lung | - |
Rattus norvegicus | - |
3.4.22.24 | small intestine | - |
Rattus norvegicus | - |
3.4.22.24 | spleen | - |
Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.4.22.24 | additional information | - |
- |
Rattus norvegicus |
EC Number | Storage Stability | Organism |
---|---|---|
3.4.22.24 | -70°C, in 50 mM sodium phosphate buffer, pH 6.5, 25 mM NaCl, 12.5% glycerol, 1 mM DTT, at least 2 months | Rattus norvegicus |
3.4.22.24 | 4°C, at somewhat higher ionic strength than 50 mM sodium phosphate, pH 6.5, 25 mM NaCl, 12.5% glycerol, 1 mM DTT, inactivation within 1 week | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.22.24 | Acid-denatured hemoglobin + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.4.22.24 | azocasein + H2O | - |
Rattus norvegicus | ? | - |
? | |
3.4.22.24 | additional information | cytosolic or mitochondrial forms of aspartate aminotransferase | Rattus norvegicus | ? | - |
? | |
3.4.22.24 | additional information | Nalpha-benzoyl-(DL)-Arg-beta-naphthylamide | Rattus norvegicus | ? | - |
? | |
3.4.22.24 | additional information | little or no activity at 0øC with glucose 6-phosphate dehydrogenase, native ribonuclease A, native bovine serum albumin, cytochrome c or oxidized insulin B-chain | Rattus norvegicus | ? | - |
? | |
3.4.22.24 | Performic acid-oxidized ribonuclease A + H2O | - |
Rattus norvegicus | Hydrolyzed performic acid-oxidized ribonuclease A | - |
? | |
3.4.22.24 | Tyrosine aminotransferase + H2O | involved in generation of isozymic forms of tyrosine transferase | Rattus norvegicus | ? | - |
? | |
3.4.22.24 | Tyrosine aminotransferase form I + H2O | enzyme converses native larger subunit to smaller subunit | Rattus norvegicus | Tyrosine aminotransferase form II and III + acidic peptide of MW 4500 peptide | - |
? | |
3.4.22.24 | Tyrosine aminotransferase form I + H2O | thereby generating multiple forms of tyrosine aminotransferase | Rattus norvegicus | Tyrosine aminotransferase form II and III + acidic peptide of MW 4500 peptide | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.4.22.24 | monomer | SDS-PAGE | Rattus norvegicus |
3.4.22.24 | monomer | 1 * 35000, liver | Rattus norvegicus |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.4.22.24 | 37 | - |
15 min, pH 6.5, 50% loss of activity | Rattus norvegicus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.4.22.24 | 6.9 | - |
0°C | Rattus norvegicus |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
3.4.22.24 | 5 | 8 | active in this range, negligible below pH 5 and above pH 8 | Rattus norvegicus |
EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|---|
3.4.22.24 | 6.5 | - |
15 min, 37°C, 50% loss of activity | Rattus norvegicus |
3.4.22.24 | 7 | - |
above, 0°C, 1.25% glycerol, rapid loss of activity | Rattus norvegicus |
3.4.22.24 | 7.8 | - |
20 min, 0°C, inactivation | Rattus norvegicus |