Literature summary extracted from

Lenney, J.F.; Liao, J.R.; Sugg, S.L.; Gopalakrishnan, V.; Wong, H.C.H.; Ouye, K.H.; Chan, P.W.H.
Low molecular weight inhibitors of cathepsins B, H and T in human serum, synovial fluid and CSF (1982), Biochem. Biophys. Res. Commun., 108, 1581-1587.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.22.16	Thiol proteinase inhibitor	from human serum, human lung, molecular weights: 13000 and 80000, the latter including haptoglobin, 4-7% inhibition	Homo sapiens
3.4.22.24	Low molecular weight thiol proteinase inhibitor fractions	of human or rat serum, human synovial fluid and cerebrospinal fluid, MW 17000	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.22.16	Homo sapiens	-	-	-
3.4.22.24	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.22.16	liver	-	Homo sapiens	-
3.4.22.24	kidney	-	Rattus norvegicus	-
3.4.22.24	plasma	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.22.24	Cbz-Phe-Arg-7-amido-4-methylcoumarin + H2O	-	Rattus norvegicus	Cbz-Phe-Arg + 7-amino-4-methylcoumarin	-	?

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Release 2023.1 (January 2023)