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Literature summary extracted from

  • Walls, A.F.; Bennett, A.R.; Sueiras-Diaz, J.; Olsson, H.
    The kininogenase activity of human mast cell tryptase (1992), Biochem. Soc. Trans., 20, 260S.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.59 antipain
-
 Homo sapiens
3.4.21.59 benzamidine
-
 Homo sapiens
3.4.21.59 leupeptin
-
 Homo sapiens
3.4.21.59 N-tosyl-L-Lys chloromethyl ketone
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.21.59 additional information
-
 additional information
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.59 additional information Homo sapiens tryptase may have kallikrein-like activity under physiological conditions, tryptase could be of importance in the generation of kinnins subsequent to mast cell activation ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.59 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.59 mast cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.59 additional information kininogenase activity Homo sapiens ?
-
 ?
3.4.21.59 additional information tryptase may have kallikrein-like activity under physiological conditions, tryptase could be of importance in the generation of kinnins subsequent to mast cell activation Homo sapiens ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.21.59 8
-
-
 Homo sapiens