Any feedback?
Literature summary extracted from
- Purification and properties of N-formylmethionine aminopeptidase from rat liver (1980), Biochim. Biophys. Acta, 616, 60-67.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.19.7 | Cd2+ | - |
Rattus norvegicus |  |
| 3.4.19.7 | Cu2+ | moderate | Rattus norvegicus | |
| 3.4.19.7 | Fe2+ | moderate | Rattus norvegicus | |
| 3.4.19.7 | heavy metal ions | - |
Rattus norvegicus | |
| 3.4.19.7 | Hg2+ | - |
Rattus norvegicus | |
| 3.4.19.7 | additional information | not: EDTA | Rattus norvegicus | |
| 3.4.19.7 | NEM | weak | Rattus norvegicus | |
| 3.4.19.7 | phenylmethanesulfonyl fluoride | weak | Rattus norvegicus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.19.7 | 0.03 | - |
N-Formyl-Met-Leu | - |
Rattus norvegicus | |
| 3.4.19.7 | 0.2 | - |
N-Formyl-Met 2-naphthylamide | - |
Rattus norvegicus | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.19.7 | Cl- | activates | Rattus norvegicus | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.19.7 | 72000 | - |
4 * 72000, SDS-PAGE | Rattus norvegicus |
| 3.4.19.7 | 290000 | - |
rat, gel filtration | Rattus norvegicus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.19.7 | Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.19.7 | - |
Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.19.7 | liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.4.19.7 | additional information | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.19.7 | additional information | highly specific for N-formyl-Met peptides, will not cleave methionyl peptides or N-formyl derivatives of amino acids other than methionine | Rattus norvegicus | ? | - |
? | |
| 3.4.19.7 | N-Formyl-Met 2-naphthylamide + H2O | - |
Rattus norvegicus | N-Formyl-Met + 2-naphthylamine | - |
? | |
| 3.4.19.7 | N-Formyl-Met-Leu + H2O | - |
Rattus norvegicus | N-Formyl-Met + Leu | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.19.7 | tetramer | 4 * 72000, SDS-PAGE | Rattus norvegicus |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.19.7 | 37 | - |
assay at | Rattus norvegicus |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.19.7 | 230 | - |
N-Formyl-Met 2-naphthylamide | - |
Rattus norvegicus | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.19.7 | 7.8 | - |
- |
Rattus norvegicus |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.19.7 | 6 | 10 | 6: about 40% of activity maximum, 10: about 50% of activity maximum | Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
