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Literature summary extracted from

  • Wang, W.; Hendricks, D.F.; Scharpe, S.S.
    Carboxypeptidase U, a plasma carboxypeptidase with high affinity for plasminogen (1994), J. Biol. Chem., 269, 15937-15944.
    View publication on PubMed

General Stability

EC Number General Stability Organism
3.4.17.20 very unstable in gel filtration procedures Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.17.20 1,10-phenanthroline
-
 Homo sapiens
3.4.17.20 2-Guanidinoethylmercaptosuccinic acid i.e. GEMSA Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.17.20 1.12
-
 hippuryl-L-Arg
-
 Homo sapiens
3.4.17.20 1.45
-
 Hippuryl-L-Lys
-
 Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.17.20 Zn2+ metalloproteinase Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.17.20 53000
-
 x * 53000, SDS-PAGE, gel filtration after treatment with guanidine-HCL Homo sapiens
3.4.17.20 435000
-
 gel permeation chromatography Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.20 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.17.20
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.17.20 plasma
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.17.20 2000
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.20 Hippuryl-L-Arg + H2O
-
 Homo sapiens Hippuric acid + L-Arg
-
 ?
3.4.17.20 Hippuryl-L-argininic acid + H2O
-
 Homo sapiens Hippuric acid + argininic acid
-
 ?
3.4.17.20 Hippuryl-L-Lys + H2O
-
 Homo sapiens Hippuric acid + L-Lys
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.17.20 ? x * 53000, SDS-PAGE, gel filtration after treatment with guanidine-HCL Homo sapiens

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.4.17.20 4
-
 at 4°C higher stability than at 30°C, but nevertheless unstable Homo sapiens
3.4.17.20 30
-
 half-life 60 min Homo sapiens
3.4.17.20 37
-
 30 min, 80% loss of activity Homo sapiens