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Literature summary extracted from

  • Hedeager-Sorensen, S.; Kenny, A.J.
    Proteins of the kidney microvillar membrane. Purification and properties of carboxypeptidase P from pig kidneys (1985), Biochem. J., 229, 251-257.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.17.16 1,10-phenanthroline
-
 Sus scrofa
3.4.17.16 EDTA
-
 Sus scrofa
3.4.17.16 Zn2+ 0.5 mM activates, inhibition above Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.17.16 4.1
-
 Benzyloxycarbonyl-Pro-Met
-
 Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.17.16 Mn2+ MnCl2, 1 mM, is necessary for maximal activity Sus scrofa
3.4.17.16 Zn each of the two subunits contains one Zn atom, ZnSO4, 0.5 mM, limited activation in absence of MnCl2, strong inhibition above 0.5 mM Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.17.16 135000
-
 2 * 135000, pig, SDS-PAGE Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.16 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.17.16
-
 Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.17.16 kidney
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.17.16 additional information
-
-
 Sus scrofa

Storage Stability

EC Number Storage Stability Organism
3.4.17.16 -20°C, unstable Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.16 Ala-Ala-Ala-Ala + H2O
-
 Sus scrofa Ala-Ala-Ala + Ala
-
 ?
3.4.17.16 Benzyloxycarbonyl-Ala-Phe + H2O
-
 Sus scrofa Benzyloxycarbonyl-Ala + Phe
-
 ?
3.4.17.16 Benzyloxycarbonyl-Pro-Ala + H2O
-
 Sus scrofa Benzyloxycarbonyl-Pro + Ala
-
 ?
3.4.17.16 Benzyloxycarbonyl-Pro-Met + H2O
-
 Sus scrofa Benzyloxycarbonyl-Pro + Met
-
 ?
3.4.17.16 Benzyloxycarbonyl-Pro-Phe + H2O
-
 Sus scrofa Benzyloxycarbonyl-Pro + Phe
-
 ?
3.4.17.16 Val-Ala-Ala-Phe + H2O
-
 Sus scrofa Val-Ala-Ala + Phe
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.17.16 dimer 2 * 135000, pig, SDS-PAGE Sus scrofa

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.4.17.16 20.5
-
 Benzyloxycarbonyl-Pro-Met
-
 Sus scrofa