EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.1.1.139 | tryptophan | 2fold increase at 0.2 mM | Streptomyces longisporoflavus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.1.1.139 | 1H-indole | 62% activity left at 1.1 mM | Streptomyces longisporoflavus | |
2.1.1.139 | 3'-demethylstaurosporine | 69% activity at 1.1 mM | Streptomyces longisporoflavus | |
2.1.1.139 | anthranilate | 75% activity left at 1.1 mM | Streptomyces longisporoflavus | |
2.1.1.139 | Indole-3-pyruvate | 44% activity left at 1.1 mM | Streptomyces longisporoflavus | |
2.1.1.139 | S-(5'-adenosyl)-L-homocysteine | strong inhibition, 8% activity left at 1.1 mM, probably competitive inhibition | Streptomyces longisporoflavus | |
2.1.1.139 | tryptophan | 64% activity left at 1.1 mM | Streptomyces longisporoflavus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.1.139 | S-adenosyl-L-methionine + 3'-demethylstaurosporine | Streptomyces longisporoflavus | - |
S-adenosyl-L-homocysteine + staurosporine | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.1.1.139 | Streptomyces longisporoflavus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.1.1.139 | anion exchange chromatography, partial purification | Streptomyces longisporoflavus |
EC Number | Storage Stability | Organism |
---|---|---|
2.1.1.139 | 4°C, 6 days, 80% | Streptomyces longisporoflavus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.1.139 | S-adenosyl-L-methionine + 3'-demethylstaurosporine | - |
Streptomyces longisporoflavus | S-adenosyl-L-homocysteine + staurosporine | - |
? |