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Literature summary extracted from

  • Schach, S.; Schwarz, G.; Fetzner, S.; Lingens, F.
    Microbial metabolism of quinoline and related compounds. XVII. Degradation of 3-methylquinoline by Comamonas testosteroni 63 (1993), Biol. chem., 374, 175 - 181.
    View publication on PubMed

General Stability

EC Number General Stability Organism
1.3.1.65 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline is unstable in presence of air Comamonas testosteroni

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.1.65 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH Comamonas testosteroni degradation pathway for 3-methylquinoline 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+
-
 r
1.3.1.65 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH Comamonas testosteroni 63 degradation pathway for 3-methylquinoline 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.65 Comamonas testosteroni
-
-
-
1.3.1.65 Comamonas testosteroni 63
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.65 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH
-
 Comamonas testosteroni 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+
-
 r
1.3.1.65 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH degradation pathway for 3-methylquinoline Comamonas testosteroni 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+
-
 r
1.3.1.65 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH
-
 Comamonas testosteroni 63 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+
-
 r
1.3.1.65 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH degradation pathway for 3-methylquinoline Comamonas testosteroni 63 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+
-
 r

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.3.1.65 30
-
 no growth at 41°C Comamonas testosteroni

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.65 NADH
-
 Comamonas testosteroni