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Literature summary extracted from
- Glyceraldehyde-3-phosphate dehydrogenase from human tissues (1982), Methods Enzymol., 89, 301-305.
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 1.2.1.12 | - |
Homo sapiens |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.2.1.12 | NAD+ | competitive against NADH | Homo sapiens |  |
| 1.2.1.12 | NADH | competitive against NAD+ | Homo sapiens | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.2.1.12 | additional information | - |
additional information | - |
Homo sapiens |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.2.1.12 | 142000 | - |
equilibrium sedimentation | Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.2.1.12 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.2.1.12 | - |
Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.2.1.12 | brain | - |
Homo sapiens | - |
| 1.2.1.12 | erythrocyte | - |
Homo sapiens | - |
| 1.2.1.12 | heart | - |
Homo sapiens | - |
| 1.2.1.12 | kidney | - |
Homo sapiens | - |
| 1.2.1.12 | liver | - |
Homo sapiens | - |
| 1.2.1.12 | lung | - |
Homo sapiens | - |
| 1.2.1.12 | muscle | skeletal muscle | Homo sapiens | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.2.1.12 | 68.1 | - |
enzyme from liver | Homo sapiens |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.2.1.12 | 3-phospho-D-glyceroyl phosphate + NADH | - |
Homo sapiens | D-glyceraldehyde 3-phosphate + phosphate + NAD+ | - |
? | |
| 1.2.1.12 | 3-phospho-D-glyceroyl phosphate + NADH | - |
Homo sapiens | D-glyceraldehyde 3-phosphate + phosphate + NAD+ | - |
r | |
| 1.2.1.12 | D-glyceraldehyde 3-phosphate + arsenate + NAD+ | - |
Homo sapiens | 3-phospho-D-glyceroyl arsenate + NADH | - |
? | |
| 1.2.1.12 | D-glyceraldehyde 3-phosphate + phosphate + NAD+ | - |
Homo sapiens | 3-phospho-D-glyceroyl phosphate + NADH | - |
r | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.2.1.12 | 7.2 | 7.3 | reaction with 3-phospho-D-glyceroylphosphate | Homo sapiens |
| 1.2.1.12 | 8 | 8.3 | reaction with D-glyceraldehyde 3-phosphate | Homo sapiens |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.2.1.12 | NAD+ | - |
Homo sapiens | |
| 1.2.1.12 | NADH | cofactor | Homo sapiens | |
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