EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.1.3.6 | Triton X-100 | inactivates at a concentration of 0.02% | Schizophyllum commune |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.3.6 | sodium deoxycholate | - |
Schizophyllum commune | |
1.1.3.6 | Triton X-100 | inactivates at a concentration of 0.02% | Schizophyllum commune |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.3.6 | 0.33 | - |
cholesterol | - |
Schizophyllum commune |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.1.3.6 | 53000 | - |
SDS-PAGE, sedimentation equilibrium, amino acid analysis | Schizophyllum commune |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.3.6 | cholesterol + O2 | Schizophyllum commune | - |
cholest-5-en-3-one + H2O2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.3.6 | Schizophyllum commune | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.1.3.6 | - |
Schizophyllum commune |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
1.1.3.6 | cholesterol + O2 = cholest-5-en-3-one + H2O2 | bifunctional enzyme, catalyzes both the oxidation of DELTA5-ene-3beta hydroxysteroids with a trans A-B ring junction to the corresponding DELTA5-3-ketosteroid with the reduction of oxygen to hydrogen peroxide, and the isomerization to the DELTA4-3-ketosteroid | Schizophyllum commune |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.3.6 | cholesterol + O2 | - |
Schizophyllum commune | cholest-4-en-3-one + H2O2 | - |
? | |
1.1.3.6 | cholesterol + O2 | - |
Schizophyllum commune | cholest-5-en-3-one + H2O2 | - |
? | |
1.1.3.6 | dehydroepiandrosterone + O2 | - |
Schizophyllum commune | androst-5-en-3,17-dione + H2O2 | - |
? | |
1.1.3.6 | lanosterol + O2 | slow rate | Schizophyllum commune | lanosta-8,24-dien-3-one + H2O2 | - |
? | |
1.1.3.6 | pregnenolone + O2 | - |
Schizophyllum commune | 5-pregnen-3,20-dione + H2O2 | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.1.3.6 | monomer | 1 * 53000, SDS-PAGE | Schizophyllum commune |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.1.3.6 | 4 | 5 | - |
Schizophyllum commune |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.3.6 | FAD | firmly bound | Schizophyllum commune | |
1.1.3.6 | FAD | flavoprotein | Schizophyllum commune |