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Literature summary extracted from
- 2-Hydroxy fatty acid oxidases of rat kidney (1970), Biochem. Biophys. Res. Commun., 38, 470-477.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.1.1.98 | cytosol | - |
Rattus norvegicus | 5829 | - |
| 1.1.1.98 | microsome | - |
Rattus norvegicus | - |
- |
| 1.1.1.99 | cytosol | - |
Rattus norvegicus | 5829 | - |
| 1.1.1.99 | microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.98 | D-2-hydroxy fatty acid + NAD+ | Rattus norvegicus | intermediate product in the alpha-oxidation of normal and/or branched long-chain fatty acids | 2-keto fatty acid + NADH + H+ | - |
? |  |
| 1.1.1.98 | D-2-hydroxystearate + NAD+ | Rattus norvegicus | - |
2-oxostearate + NADH + H+ | - |
? | |
| 1.1.1.99 | L-2-hydroxy fatty acid + NAD+ | Rattus norvegicus | intermediate product in the alpha-oxidation of normal and/or branched long-chain fatty acids | 2-keto fatty acid + NADH + H+ | - |
? | |
| 1.1.1.99 | L-2-hydroxystearate + NAD+ | Rattus norvegicus | - |
2-oxostearate + NADH + H+ | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.98 | Rattus norvegicus | - |
- |
- |
| 1.1.1.99 | Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.1.1.98 | partial | Rattus norvegicus |
| 1.1.1.99 | partial | Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.1.1.98 | kidney | - |
Rattus norvegicus | - |
| 1.1.1.99 | kidney | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.98 | D-2-hydroxy fatty acid + NAD+ | - |
Rattus norvegicus | 2-keto fatty acid + NADH + H+ | - |
? | |
| 1.1.1.98 | D-2-hydroxy fatty acid + NAD+ | intermediate product in the alpha-oxidation of normal and/or branched long-chain fatty acids | Rattus norvegicus | 2-keto fatty acid + NADH + H+ | - |
? | |
| 1.1.1.98 | D-2-hydroxystearate + NAD+ | - |
Rattus norvegicus | 2-oxostearate + NADH + H+ | - |
? | |
| 1.1.1.99 | L-2-hydroxy fatty acid + NAD+ | - |
Rattus norvegicus | 2-keto fatty acid + NADH + H+ | - |
? | |
| 1.1.1.99 | L-2-hydroxy fatty acid + NAD+ | intermediate product in the alpha-oxidation of normal and/or branched long-chain fatty acids | Rattus norvegicus | 2-keto fatty acid + NADH + H+ | - |
? | |
| 1.1.1.99 | L-2-hydroxystearate + NAD+ | - |
Rattus norvegicus | 2-oxostearate + NADH | - |
? | |
| 1.1.1.99 | L-2-hydroxystearate + NAD+ | - |
Rattus norvegicus | 2-oxostearate + NADH + H+ | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.98 | 37 | - |
assay at | Rattus norvegicus |
| 1.1.1.99 | 37 | - |
assay at | Rattus norvegicus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.98 | 7.5 | - |
assay at | Rattus norvegicus |
| 1.1.1.99 | 7.5 | - |
assay at | Rattus norvegicus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.98 | NAD+ | - |
Rattus norvegicus | |
| 1.1.1.99 | NAD+ | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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