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Literature summary extracted from

  • Coderch, R.; Lluis, C.; Bozal, J.
    Effect of salts on D-glycerate dehydrogenase kinetic behavior (1979), Biochim. Biophys. Acta, 566, 21-31.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.1.1.81 CsCl 80 mM, 3fold increase in hydroxypyruvate reductase activity Bos taurus
1.1.1.81 KCl 80 mM, 9fold increase in hydroxypyruvate reductase activity Bos taurus
1.1.1.81 NaCl 80 mM, 8fold increase in hydroxypyruvate reductase activity, reaction rate increases with an increase in NaCl concentration up to 200 mM, but diminishes if the salt concentration is greater Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.81 NaNO3 80 mM, 50% inhibition Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.81 0.0038
-
 Hydroxypyruvate value increases with NaCl concentrations higher than 10 mM Bos taurus
1.1.1.81 0.0061
-
 NADH
-
 Bos taurus
1.1.1.81 0.22
-
 NAD+ D-glycerate oxidation, 50 mM, NaCl, pH 9 Bos taurus
1.1.1.81 0.522
-
 D-glycerate D-glycerate oxidation, 50 mM, NaCl, pH 9 Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.81 hydroxypyruvate + NAD(P)H Bos taurus
-
 D-glycerate + NAD(P)+ + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.81 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.81 3-hydroxypyruvate + NADH + H+
-
 Bos taurus D-glycerate + NAD+
-
 r
1.1.1.81 D-glycerate + NAD+
-
 Bos taurus 3-hydroxypyruvate + NADH + H+
-
 r
1.1.1.81 hydroxypyruvate + NAD(P)H
-
 Bos taurus D-glycerate + NAD(P)+ + H+
-
 ?