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Literature summary extracted from

  • Ploc, I.; Starka, L.
    Gas chromatographic study of the histochemical reaction for isopropanol dehydrogenase (1979), J. Chromatogr., 172, 374-378.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.1.1.80 diagnostics characterization of adrenal and gonadal tissue Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.80 0.00024
-
ethanol
-
Rattus norvegicus
1.1.1.80 0.00071
-
4-Methyl-1-pentanol
-
Rattus norvegicus
1.1.1.80 0.00178
-
propan-2-ol
-
Rattus norvegicus
1.1.1.80 0.00259
-
6-methyl-2-heptanol
-
Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.80 cytoplasm activity detected in mitochondria and cytoplasm Rattus norvegicus 5737
-
1.1.1.80 mitochondrion
-
Rattus norvegicus 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.80 additional information Rattus norvegicus possibly takes part in the further metabolic reactions of the fragments formed from the side-chain of the steroid hormone precursor in the adrenals or gonads ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.80 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.80 adrenal gland
-
Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.80 4-methyl-1-pentanol + NAD+
-
Rattus norvegicus 4-methyl-1-pentanal + NADH
-
?
1.1.1.80 4-methyl-1-pentanol + NADP+
-
Rattus norvegicus 4-methyl-1-pentanal + NADPH
-
?
1.1.1.80 6-methyl-2-heptanol + NAD+
-
Rattus norvegicus 6-methyl-2-heptanone + NADH + H+
-
?
1.1.1.80 6-methyl-2-heptanol + NADP+
-
Rattus norvegicus 6-methyl-2-heptanone + NADPH
-
?
1.1.1.80 ethanol + NAD+
-
Rattus norvegicus ethanal + NADH
-
?
1.1.1.80 ethanol + NADP+
-
Rattus norvegicus ethanal + NADPH + H+
-
?
1.1.1.80 additional information also acts on short-chain secondary alcohols and, slowly, on primary alcohols Rattus norvegicus ?
-
?
1.1.1.80 additional information possibly takes part in the further metabolic reactions of the fragments formed from the side-chain of the steroid hormone precursor in the adrenals or gonads Rattus norvegicus ?
-
?
1.1.1.80 propan-2-ol + NAD+ NAD+ effectively substitutes for NADP+ Rattus norvegicus acetone + NADH
-
?
1.1.1.80 propan-2-ol + NADP+
-
Rattus norvegicus acetone + NADPH
-
?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.80 6.4 7 in mitochondria Rattus norvegicus
1.1.1.80 8.2
-
in cytoplasma Rattus norvegicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.1.1.80 6 8.6
-
Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.80 NAD+ effectively substitutes for NADP+ Rattus norvegicus
1.1.1.80 NADP+
-
Rattus norvegicus