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Literature summary extracted from
- Glucose-6-phosphate dehydrogenase from cow adrenal cortex-1 (1975), Methods Enzymol., 41, 188-196.
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 1.1.1.49 | - |
Bos taurus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.49 | estrogen | - |
Bos taurus |  |
| 1.1.1.49 | p-chloromercuribenzoate | - |
Bos taurus | |
| 1.1.1.49 | progesterone | - |
Bos taurus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.1.1.49 | 0.0056 | - |
NADP+ | - |
Bos taurus | |
| 1.1.1.49 | 0.042 | - |
D-glucose 6-phosphate | cosubstrate NADP+ | Bos taurus | |
| 1.1.1.49 | 0.047 | - |
NAD+ | - |
Bos taurus | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.49 | Mg2+ | activation | Bos taurus | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.49 | 238700 | - |
ultracentrifugation | Bos taurus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.49 | D-glucose 6-phosphate + H2O + NADP+ | Bos taurus | - |
D-gluconate 6-phosphate + NADPH + H+ | 6-phosphoglucono-delta-lactone | r | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.49 | Bos taurus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.1.1.49 | - |
Bos taurus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.1.1.49 | adrenal cortex | - |
Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.49 | D-glucose 6-phosphate + H2O + NADP+ | - |
Bos taurus | D-gluconate 6-phosphate + NADPH + H+ | 6-phosphoglucono-delta-lactone | r | |
| 1.1.1.49 | D-glucose 6-phosphate + NAD+ | - |
Bos taurus | D-glucono-1,5-lactone 6-phosphate + NADH + H+ | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.49 | 37 | - |
- |
Bos taurus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.49 | 8 | 9 | - |
Bos taurus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.49 | NAD+ | - |
Bos taurus | |
| 1.1.1.49 | NADP+ | - |
Bos taurus | |
| 1.1.1.49 | NADPH | - |
Bos taurus | |
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Release 2023.1 (January 2023)
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