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Literature summary extracted from

  • Dworsky, P.; Hoffmann-Ostenhof, O.
    L-3-Aldonic acid dehydrogenase from Schwanniomyces occidentalis (1964), Acta Biochim. Pol., 9, 269-277.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.45 iodoacetate
-
Schwanniomyces occidentalis
1.1.1.45 p-chloromercuribenzoate
-
Schwanniomyces occidentalis
1.1.1.45 Phenylmercurinitrate
-
Schwanniomyces occidentalis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.45 1.1
-
NAD+ cosubstrate L-gulonate, pH 7.5 and pH 8.5 Schwanniomyces occidentalis
1.1.1.45 19
-
D-gluconate cofactor NAD+, pH 8.5 Schwanniomyces occidentalis
1.1.1.45 55
-
L-gulonate cofactor NAD+, pH 8.5 Schwanniomyces occidentalis
1.1.1.45 67
-
L-gulonate cofactor NAD+, pH 7.5 Schwanniomyces occidentalis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.45 L-gulonic acid + NAD+ Schwanniomyces occidentalis glucuronate-xylulose cycle 3-dehydro-L-gulonic acid + NADH + H+
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.45 Schwanniomyces occidentalis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.45 67% yield Schwanniomyces occidentalis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.45 D-gluconic acid + NAD+
-
Schwanniomyces occidentalis ?
-
?
1.1.1.45 D-lyxonic acid + NAD+
-
Schwanniomyces occidentalis ?
-
?
1.1.1.45 L-gulonic acid + NAD+ stereospecificity for L-configuration of the beta-carbon hydroxyl group Schwanniomyces occidentalis 3-dehydro-L-gulonic acid + NADH + H+
-
r
1.1.1.45 L-gulonic acid + NAD+ glucuronate-xylulose cycle Schwanniomyces occidentalis 3-dehydro-L-gulonic acid + NADH + H+
-
?
1.1.1.45 L-idonic acid + NAD+
-
Schwanniomyces occidentalis ?
-
?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.1.1.45 additional information
-
in solution instable, by addition of below mM of cyanide several days in the cold, minor effect through EDTA-addition Schwanniomyces occidentalis

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.45 9
-
oxidation of L-gulonic acid Schwanniomyces occidentalis

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.45 NAD+
-
Schwanniomyces occidentalis