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Literature summary extracted from

  • Prasad, M.R.; Cook, L.; Vieth, R.; Cinti, D.L.
    Rat hepatic microsomal acetoacetyl-CoA reductase. A beta-ketoacyl-CoA reductase distinct from the long chain beta-ketoacyl-CoA reductase component of the microsomal fatty acid chain elongation system (1984), J. Biol. Chem., 259, 7460-7467.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.36 0.018
-
 NADH cosubstrate acetoacetyl-Co-A Rattus norvegicus
1.1.1.36 0.021
-
 acetoacetyl-CoA cofactor NADH Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.36 cytosol
-
 Rattus norvegicus 5829
-
1.1.1.36 microsome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.36 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.36 KCl extraction Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.36 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.36 acetoacetyl-CoA + NADH + H+
-
 Rattus norvegicus D-beta-hydroxybutyryl-CoA + NAD+
-
 ?
1.1.1.36 acetoacetyl-CoA + NADPH + H+
-
 Rattus norvegicus (3R)-3-hydroxybutyryl-CoA + NADP+
-
 r

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.1.1.36 37
-
-
 Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.36 6.5 8
-
 Rattus norvegicus

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
1.1.1.36 6 8.5
-
 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.36 NADH
-
 Rattus norvegicus
1.1.1.36 NADP+
-
 Rattus norvegicus
1.1.1.36 NADPH
-
 Rattus norvegicus