Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Robinson, W.G.; Coon, M.J.
    The purification and properties of beta-hydroxyisobutyrate dehydrogenase (1956), J. Biol. Chem., 225, 511-521.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.31 HgCl2
-
 Sus scrofa
1.1.1.31 iodoacetate
-
 Sus scrofa
1.1.1.31 p-chloromercuribenzoate
-
 Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.31 0.054
-
 NAD+
-
 Sus scrofa
1.1.1.31 0.12
-
 DL-3-hydroxyisobutyrate
-
 Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.31 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.31
-
 Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.31 heart
-
 Sus scrofa
-
1.1.1.31 kidney
-
 Sus scrofa
-
1.1.1.31 liver
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.31 20.9
-
-
 Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.31 DL-3-hydroxyisobutyrate + NAD+
-
 Sus scrofa methylmalonate semialdehyde + NADH + H+
-
 r
1.1.1.31 L-3-hydroxyisobutyrate + NAD+
-
 Sus scrofa L-2-methyl-3-oxopropionate + NADH
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.31 9
-
-
 Sus scrofa

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.1.1.31 7 11
-
 Sus scrofa

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.31 NAD+
-
 Sus scrofa