Literature summary extracted from

Nielsen, N.C.; Zahler, W.L.; Fleischer, S.
Mitochondrial D-beta-hydroxybutyrate dehydrogenase. IV. Kinetic analysis of reaction mechanism (1973), J. Biol. Chem., 248, 2556-2562.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
1.1.1.30	phosphatidylcholine	-	Bos taurus

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.1.1.30	KCl	80-100 mM, 50% inhibition	Bos taurus
1.1.1.30	LiCl	80-100 mM, 50% inhibition	Bos taurus
1.1.1.30	NaCl	80-100 mM, 50% inhibition	Bos taurus
1.1.1.30	NADH	competitive vs. NAD+	Bos taurus
1.1.1.30	NH4Cl	80-100 mM, 50% inhibition	Bos taurus

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.1.1.30	(R)-3-hydroxybutanoate + NAD+	Bos taurus	-	acetoacetate + NADH	-	r

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.30	Bos taurus	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.30	(R)-3-hydroxybutanoate + NAD+	-	Bos taurus	acetoacetate + NADH	-	r

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.1.1.30	NAD+	-	Bos taurus

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Release 2023.1 (January 2023)