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Literature summary extracted from

  • Tucker, G.A.; Dawson, A.P.
    The kinetics of rat liver and heart mitochondria beta-hydroxybutyrate dehydrogenase (1979), Biochem. J., 179, 579-581.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.1.1.30 phosphatidylcholine
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.30 0.014
-
 NADH liver, soluble enzyme Rattus norvegicus
1.1.1.30 0.029
-
 NADH heart, soluble enzyme Rattus norvegicus
1.1.1.30 0.067
-
 NAD+ heart, soluble enzyme Rattus norvegicus
1.1.1.30 0.071
-
 NAD+ liver, soluble enzyme Rattus norvegicus
1.1.1.30 0.149
-
 acetoacetate liver, soluble enzyme Rattus norvegicus
1.1.1.30 0.312
-
 acetoacetate heart, soluble enzyme Rattus norvegicus
1.1.1.30 0.866
-
 (R)-3-hydroxybutanoate liver, soluble enzyme Rattus norvegicus
1.1.1.30 0.866
-
 (R)-3-hydroxybutanoate liver-soluble enzyme, at pH 8.1 and 30°C Rattus norvegicus
1.1.1.30 1.586
-
 (R)-3-hydroxybutanoate heart, soluble enzyme Rattus norvegicus
1.1.1.30 1.586
-
 (R)-3-hydroxybutanoate heart-soluble enzyme, at pH 8.1 and 30°C Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.30 (R)-3-hydroxybutanoate + NAD+ Rattus norvegicus
-
 acetoacetate + NADH
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.30 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.30 heart
-
 Rattus norvegicus
-
1.1.1.30 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.30 (R)-3-hydroxybutanoate + NAD+
-
 Rattus norvegicus acetoacetate + NADH
-
 r
1.1.1.30 (R)-3-hydroxybutanoate + NAD+
-
 Rattus norvegicus acetoacetate + NADH + H+
-
 r

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.30 NAD+
-
 Rattus norvegicus