EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.30 | phosphatidylcholine | - |
Paracoccus denitrificans |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.30 | (DL)-2-hydroxybutyrate | 5 mM, pH 8.5, 25°, 69% inhibition | Paracoccus denitrificans | |
1.1.1.30 | (DL)-lactate | 5 mM, pH 8.5, 25°C, 65% inhibition | Paracoccus denitrificans | |
1.1.1.30 | ADP-ribose | competitive inhibition vs. coenzyme, noncompetitive vs. substrate | Paracoccus denitrificans | |
1.1.1.30 | Butyrate | 5 mM, pH 8.5, 25°C, 22% inhibition | Paracoccus denitrificans | |
1.1.1.30 | D-lactate | 5 mM, pH 8.5, 25°, 85% inhibition, uncompetitive vs. coenzyme, competitive vs. substrate | Paracoccus denitrificans | |
1.1.1.30 | L-3-hydroxybutyrate | 5 mM, pH 8.5, 25°C, 23% inhibition; 5 mM, pH 8.5, 25°C, 32% inhibition | Paracoccus denitrificans | |
1.1.1.30 | propionate | 5 mM, pH 8.5, 25°C, 9% inhibition | Paracoccus denitrificans |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.30 | (R)-3-hydroxybutanoate + NAD+ | Paracoccus denitrificans | - |
acetoacetate + NADH | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.30 | Paracoccus denitrificans | - |
enzyme shows hysteresis, lag phase in progress curve | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.30 | (R)-3-hydroxybutanoate + NAD+ | - |
Paracoccus denitrificans | acetoacetate + NADH | - |
r |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.1.1.30 | 7 | - |
reduction of acetoacetate | Paracoccus denitrificans |
1.1.1.30 | 8.5 | - |
oxidation of beta-hydroxybutyrate | Paracoccus denitrificans |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.30 | NAD+ | - |
Paracoccus denitrificans |