Any feedback?
Literature summary extracted from
- Lactate dehydrogenase in tissue extracts of the land snail, Helix aspersa: unique adaptation of LDH subunits in a facultative anaerobe (1977), Comp. Biochem. Physiol. B, 56, 181-187.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.28 | pyruvate | - |
Cornu aspersum |  |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 1.1.1.28 | 0.015 | - |
NADH | - |
Cornu aspersum | |
| 1.1.1.28 | 0.02 | - |
NAD+ | - |
Cornu aspersum | |
| 1.1.1.28 | 0.42 | - |
pyruvate | - |
Cornu aspersum | |
| 1.1.1.28 | 3.2 | - |
(R)-lactate | - |
Cornu aspersum | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.28 | 34000 | - |
4 * 34000, SDS-PAGE | Cornu aspersum |
| 1.1.1.28 | 140000 | - |
gel filtration | Cornu aspersum |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.28 | (R)-lactate + NAD+ | Cornu aspersum | - |
pyruvate + NADH | - |
r | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.1.1.28 | Cornu aspersum | - |
land snail | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.1.1.28 | brain | - |
Cornu aspersum | - |
| 1.1.1.28 | foot | - |
Cornu aspersum | - |
| 1.1.1.28 | heart | - |
Cornu aspersum | - |
| 1.1.1.28 | hepatopancreas | - |
Cornu aspersum | - |
| 1.1.1.28 | kidney | - |
Cornu aspersum | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.1.1.28 | (R)-lactate + NAD+ | - |
Cornu aspersum | pyruvate + NADH | - |
r | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.1.1.28 | tetramer | 4 * 34000, SDS-PAGE | Cornu aspersum |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.1.1.28 | 6.4 | - |
reduction of pyruvate | Cornu aspersum |
| 1.1.1.28 | 9 | - |
oxidation of (R)-lactate | Cornu aspersum |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.1.1.28 | NAD+ | - |
Cornu aspersum | |
| 1.1.1.28 | NADH | - |
Cornu aspersum | |
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Release 2023.1 (January 2023)
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