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Literature summary extracted from

  • Hensel, R.; Mayr, U.; Fujiki, H.; Kandler, O.
    Comparative studies of lactate dehydrogenases in lactic acid bacteria. Amino-acid composition of an active-site region and chemical properties of the L-lactate dehydrogenase of Lactobacillus casei, Lactobacillus curvatus, Lactobacillus plantarum, and Lactobacillus acidophilus (1977), Eur. J. Biochem., 80, 83-92.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.27 iodoacetate
-
 Lacticaseibacillus casei
1.1.1.27 iodoacetate
-
 Lactobacillus acidophilus
1.1.1.27 iodoacetate no effect Latilactobacillus curvatus
1.1.1.27 p-hydroxymercuribenzoate
-
 Lacticaseibacillus casei
1.1.1.27 p-hydroxymercuribenzoate slight Lactobacillus acidophilus

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.27 Lacticaseibacillus casei
-
-
-
1.1.1.27 Lactiplantibacillus plantarum
-
-
-
1.1.1.27 Lactobacillus acidophilus
-
-
-
1.1.1.27 Latilactobacillus curvatus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.27
-
 Lactiplantibacillus plantarum
1.1.1.27
-
 Lacticaseibacillus casei
1.1.1.27
-
 Latilactobacillus curvatus
1.1.1.27
-
 Lactobacillus acidophilus

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.27 2350
-
-
 Lactiplantibacillus plantarum
1.1.1.27 2460
-
-
 Lactobacillus acidophilus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.27 (S)-lactate + NAD+
-
 Lactiplantibacillus plantarum pyruvate + NADH + H+
-
 r
1.1.1.27 (S)-lactate + NAD+
-
 Lacticaseibacillus casei pyruvate + NADH + H+
-
 r
1.1.1.27 (S)-lactate + NAD+
-
 Latilactobacillus curvatus pyruvate + NADH + H+
-
 r
1.1.1.27 (S)-lactate + NAD+
-
 Lactobacillus acidophilus pyruvate + NADH + H+
-
 r
1.1.1.27 pyruvate + NADH + H+
-
 Lactiplantibacillus plantarum (S)-lactate + NAD+
-
 r
1.1.1.27 pyruvate + NADH + H+
-
 Lacticaseibacillus casei (S)-lactate + NAD+
-
 r
1.1.1.27 pyruvate + NADH + H+
-
 Latilactobacillus curvatus (S)-lactate + NAD+
-
 r
1.1.1.27 pyruvate + NADH + H+
-
 Lactobacillus acidophilus (S)-lactate + NAD+
-
 r

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.27 NAD+ coenzyme Lactiplantibacillus plantarum
1.1.1.27 NAD+ coenzyme Lacticaseibacillus casei
1.1.1.27 NAD+ coenzyme Latilactobacillus curvatus
1.1.1.27 NAD+ coenzyme Lactobacillus acidophilus
1.1.1.27 NADH coenzyme Lactiplantibacillus plantarum
1.1.1.27 NADH coenzyme Lacticaseibacillus casei
1.1.1.27 NADH coenzyme Latilactobacillus curvatus
1.1.1.27 NADH coenzyme Lactobacillus acidophilus