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Literature summary extracted from

  • Sok, D.E.; Kang, J.B.; Shin, H.D.
    15-Hydroxyeicosatetraenoic acid dehydrogenase activity in microsomal fraction of mouse liver homogenate (1988), Biochem. Biophys. Res. Commun., 156, 524-529.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.232 0.0083
-
 (15S)-15-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid
-
 Mus musculus
1.1.1.232 0.06
-
 NAD+
-
 Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.232 microsome tightly bound to membranes Mus musculus
-
-

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.232 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.232 liver
-
 Mus musculus
-

Storage Stability

EC Number Storage Stability Organism
1.1.1.232 4°C enzyme in microsomal fraction very stable, cytosolic and mitochondrial fractions more than 90% loss of activity within 1 day Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.232 (15S)-15-hydroxy-5,8,11-cis-13-trans-eicosatetraenoate + NAD(P)+
-
 Mus musculus 15-oxo-5,8,11-cis-13-trans-eicosatetraenoate + NAD(P)H
-
 ?
1.1.1.232 15(S)-15-hydroxy-5,8,11-cis-13-trans-icosatetranoate + NAD+
-
 Mus musculus 15-oxo-5,8,11-cis-13-trans-icosatetraenoate + NADH + H+
-
 r

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.232 9.8
-
-
 Mus musculus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.1.1.232 7.6 11.2
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.232 NAD+ almost the same reaction rates with NAD+ and NADP+ Mus musculus
1.1.1.232 NADP+ almost the same reaction rates with NAD+ and NADP+ Mus musculus