EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.21 | (NH4)2SO4 | 0.1 M | Homo sapiens | |
1.1.1.21 | (NH4)2SO4 | 0.1 M | Rattus norvegicus | |
1.1.1.21 | (NH4)2SO4 | wild type and recombinant from Escherichia coli | Homo sapiens | |
1.1.1.21 | (NH4)2SO4 | wild type and recombinant from Escherichia coli | Rattus norvegicus | |
1.1.1.21 | Na2SO4 | 0.1 M, wild type and recombinant from E.coli | Homo sapiens | |
1.1.1.21 | Na2SO4 | 0.1 M, wild type and recombinant from E.coli | Rattus norvegicus |
EC Number | Cloned (Comment) | Organism |
---|---|---|
1.1.1.21 | expression in Escherichia coli | Homo sapiens |
1.1.1.21 | expression in Escherichia coli | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.21 | (S)-6-fluorospiro[chroman-4,5'-imidazolidine]-2',4'-dione | wild type and recombinant from E. coli | Homo sapiens | |
1.1.1.21 | (S)-6-fluorospiro[chroman-4,5'-imidazolidine]-2',4'-dione | wild type and recombinant from E. coli | Rattus norvegicus | |
1.1.1.21 | Cl- | 0.2 M, wild type and recombinant from E. coli | Homo sapiens | |
1.1.1.21 | Cl- | 0.2 M, wild type and recombinant from E. coli | Rattus norvegicus | |
1.1.1.21 | N-[[6-methoxy-5(trifluoromethyl)-1-naphthalenyl]thioxomethyl]-N-methylglycine | wild type and recombinant from E. coli | Homo sapiens | |
1.1.1.21 | N-[[6-methoxy-5(trifluoromethyl)-1-naphthalenyl]thioxomethyl]-N-methylglycine | wild type and recombinant from E. coli | Rattus norvegicus | |
1.1.1.21 | ponalrestat | wild type and recombinant from E. coli | Homo sapiens | |
1.1.1.21 | ponalrestat | wild type and recombinant from E. coli | Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.1.1.21 | 0.046 | - |
DL-glyceraldehyde | - |
Homo sapiens | |
1.1.1.21 | 0.047 | - |
DL-glyceraldehyde | recombinant from E. coli | Homo sapiens | |
1.1.1.21 | 0.08 | - |
DL-glyceraldehyde | - |
Rattus norvegicus | |
1.1.1.21 | 0.12 | - |
DL-glyceraldehyde | recombinant from E. coli | Rattus norvegicus | |
1.1.1.21 | 4.8 | - |
D-glucuronate | - |
Homo sapiens | |
1.1.1.21 | 6.4 | - |
D-glucuronate | recombinant from E. coli | Homo sapiens | |
1.1.1.21 | 8.2 | - |
D-xylose | - |
Homo sapiens | |
1.1.1.21 | 8.7 | - |
D-xylose | recombinant from E. coli | Homo sapiens | |
1.1.1.21 | 13.5 | - |
D-xylose | - |
Rattus norvegicus | |
1.1.1.21 | 13.9 | - |
D-glucuronate | recombinant from E. coli | Rattus norvegicus | |
1.1.1.21 | 16.8 | - |
D-xylose | recombinant from E. coli | Rattus norvegicus | |
1.1.1.21 | 19.2 | - |
D-glucuronate | - |
Rattus norvegicus | |
1.1.1.21 | 42.9 | - |
D-galactose | recombinant from E. coli | Homo sapiens | |
1.1.1.21 | 46.7 | - |
D-galactose | - |
Homo sapiens | |
1.1.1.21 | 78 | - |
D-galactose | recombinant from E. coli | Rattus norvegicus | |
1.1.1.21 | 83 | - |
D-galactose | - |
Rattus norvegicus | |
1.1.1.21 | 86.8 | - |
D-glucose | - |
Homo sapiens | |
1.1.1.21 | 98.1 | - |
D-glucose | recombinant from E. coli | Homo sapiens | |
1.1.1.21 | 204 | - |
D-glucose | - |
Rattus norvegicus | |
1.1.1.21 | 281 | - |
D-glucose | recombinant from E. coli | Rattus norvegicus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.1.1.21 | Li2SO4 | 0.1 M activation wild type and recombinant from E. coli | Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.1.1.21 | 38000 | - |
? * 38000, SDS-PAGE | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.1.1.21 | Homo sapiens | - |
- |
- |
1.1.1.21 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.1.1.21 | wild type and expressed in Escherichia coli | Homo sapiens |
1.1.1.21 | wild type and expressed in Escherichia coli | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.1.1.21 | lens | - |
Homo sapiens | - |
1.1.1.21 | lens | - |
Rattus norvegicus | - |
1.1.1.21 | placenta | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.1.1.21 | alditol + NAD(P)+ | - |
Homo sapiens | aldose + NAD(P)H | - |
r | |
1.1.1.21 | alditol + NAD(P)+ | - |
Rattus norvegicus | aldose + NAD(P)H | - |
r | |
1.1.1.21 | aldose + NAD(P)H | - |
Homo sapiens | alditol + NAD(P)+ | - |
r | |
1.1.1.21 | aldose + NAD(P)H | - |
Rattus norvegicus | alditol + NAD(P)+ | - |
r | |
1.1.1.21 | D-galactose + NAD(P)H | - |
Homo sapiens | dulcitol + NAD(P)+ | - |
r | |
1.1.1.21 | D-galactose + NAD(P)H | - |
Rattus norvegicus | dulcitol + NAD(P)+ | - |
r | |
1.1.1.21 | D-glucose + NAD(P)H | - |
Homo sapiens | sorbitol + NAD(P)+ | - |
r | |
1.1.1.21 | D-glucose + NAD(P)H | - |
Rattus norvegicus | sorbitol + NAD(P)+ | - |
r | |
1.1.1.21 | D-glucuronate + NAD(P)H | - |
Homo sapiens | ? | - |
r | |
1.1.1.21 | D-glucuronate + NAD(P)H | - |
Rattus norvegicus | ? | - |
r | |
1.1.1.21 | D-xylose + NAD(P)H | - |
Homo sapiens | xylitol + NAD(P)+ | - |
r | |
1.1.1.21 | D-xylose + NAD(P)H | - |
Rattus norvegicus | xylitol + NAD(P)+ | - |
r | |
1.1.1.21 | DL-glyceraldehyde + NAD(P)H | - |
Homo sapiens | glycerol + NAD(P)+ | - |
r | |
1.1.1.21 | DL-glyceraldehyde + NAD(P)H | - |
Rattus norvegicus | glycerol + NAD(P)+ | - |
r |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.1.1.21 | More | ? * 38000, SDS-PAGE | Homo sapiens |