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Literature summary extracted from

  • Maret, W.
    Human sorbitol dehydrogenase - a secondary alcohol dehydrogenase with distinct pathophysiological roles, pH dependent kinetic studies (1996), Adv. Exp. Med. Biol., , 383-393.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.14 1
-
 D-xylulose
-
 Homo sapiens
1.1.1.14 25
-
 L-erythrulose
-
 Homo sapiens
1.1.1.14 34
-
 D-ribulose
-
 Homo sapiens
1.1.1.14 140
-
 D-fructose
-
 Homo sapiens
1.1.1.14 800
-
 L-sorbose
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.14 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.14 D-fructose + NADH + H+
-
 Homo sapiens D-sorbitol + NAD+
-
 ?
1.1.1.14 D-psicose + NADH
-
 Homo sapiens ?
-
 ?
1.1.1.14 D-ribulose + NADH
-
 Homo sapiens ?
-
 ?
1.1.1.14 D-sorbitol + NAD+
-
 Homo sapiens D-fructose + NADH + H+
-
 ?
1.1.1.14 D-sorbose + NADH low activity Homo sapiens ?
-
 ?
1.1.1.14 D-tagatose + NADH
-
 Homo sapiens D-galactitol + NAD+
-
 ?
1.1.1.14 D-xylulose + NADH
-
 Homo sapiens ?
-
 ?
1.1.1.14 L-erythrulose + NADH
-
 Homo sapiens ?
-
 ?
1.1.1.14 L-sorbose + NADH
-
 Homo sapiens ?
-
 ?

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
1.1.1.14 6
-
 loses zinc at lower pH Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.14 NAD+
-
 Homo sapiens
1.1.1.14 NADH
-
 Homo sapiens