Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Schnöpp, W.; Sorger, H.; Kleber, H-P.; Aurich, H.
    Kinetische Untersuchungen zum Reaktionsmechanismus der Carnitindehydrogenase aus Pseudomonas aeruginosa (1969), Eur. J. Biochem., 10, 56-60.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.108 3-deydrocarnitine competitive inhibition vs. L-carnitine Pseudomonas aeruginosa
1.1.1.108 NADH competitive inhibition vs. NAD+ Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.108 (R)-3-hydroxy-4-trimethylaminobutyrate + NAD+ Pseudomonas aeruginosa
-
 3-dehydrocarnitine + NADH + H+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.108 Pseudomonas aeruginosa
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.108 200
-
 oxidation of L-carnitine Pseudomonas aeruginosa
1.1.1.108 600
-
 reduction of 3-dehydrocarnitine Pseudomonas aeruginosa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.108 (R)-3-hydroxy-4-trimethylaminobutyrate + NAD+
-
 Pseudomonas aeruginosa 3-dehydrocarnitine + NADH + H+
-
 r
1.1.1.108 carnitine + NAD+
-
 Pseudomonas aeruginosa 3-dehydrocarnitine + NADH + H+
-
 r

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.108 NAD+
-
 Pseudomonas aeruginosa